Avinza is indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.
Limitations of Use
- Because of the risks of addiction, abuse, and misuse with opioids, even at recommended doses, and because of the greater risks of overdose and death with extended-release opioid formulations, reserve Avinza for use in patients for whom alternative treatment options (e.g., non-opioid analgesics or immediate-release opioids) are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain.
- Avinza is not indicated as an as-needed (prn) analgesic.
- Along with its needed effects, morphine (the active ingredient contained in Avinza) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking morphine:
- Blurred vision
- bulging soft spot on the head of an infant
- burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
- change in the ability to see colors, especially blue or yellow
- chest pain or discomfort
- decreased urination
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast, pounding, or irregular heartbeat or pulse
- hives, itching, or skin rash
- increased sweating
- loss of appetite
- pounding in the ears
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- severe constipation
- severe vomiting
- shakiness in the legs, arms, hands, or feet
- slow heartbeat
- stomach pain
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